The study looks at the readiness of the BSED Biological Science Majors to teach Grades 11 and 12 based on the teacher competencies demanded by the Senior High School Curriculum. More specifically, the study identified the essential teacher competencies in terms of content and pedagogy that are needed to effectively implement the DepEd prescribed curriculum for Senior High School. The study found that the existing BSED Biological Science Curriculum is only minimally responsive to the teacher competencies demanded by the Senior High School Curriculum. Based on the curriculum mapping done, it was found that the essential teacher competencies needed to be strengthened are critical thinking skills, research methodology and writing skills, media and literacy skills, and scientific thinking skills. Integration and assessment are likewise areas that are critical for effective implementation of the Senior High School Curriculum. Among the recommendations include revising the existing BSED Biological Science Teacher Education Curriculum to make the content of certain subjects broader in scope, increasing the complexity of competencies in technology-related skills, including a Media and Information Literacy subject, and reviewing the qualifications and competencies of the existing Teacher Education Professors to ensure that competent Grade 11 and Grade 12 teachers are produced by SY 2016-2017.